Each cancer cell line offers unique advantages and limitations. This article compares two highly used models — MDA-MB-231 and A549 cells — and explains when to apply each.
Breast Cancer vs Lung Cancer
MDA-MB-231 cells model aggressive triple-negative breast cancer, optimal for metastasis studies. A549 cells represent lung adenocarcinoma, widely used in toxicology and drug screening.
Strengths and Limitations
Each cell line has strengths in specific pathways, from EMT transition to oxidative stress modeling.
